Papers
2024 Amemori, S., Graybiel, A.M., and Amemori, K. (2024) Cingulate microstimulation induces negative decision-making via reduced top-down influence on primate fronto-cingulo-striatal network. Nat. Commun., in press. 2023 Matsushima, A., Pineda, S.S., Crittenden, J.R., Lee, H., Galani, K., Mantero, J., Tombaugh, G., Kellis, M., Heiman, M., and Graybiel, A.M. (2023) Transcriptional vulnerabilities of striatal neurons in human and rodent models of Huntington’s disease. Nat. Commun., 14:282 Graybiel, A.M. and Matsushima, A. (2023) Striosomes and matrisomes: scaffolds for dynamic coupling of volition and action. Annu. Rev. Neurosci., 46:359-380 Kuo, H.-Y., Chen, S.-Y., Huang, R.-C., Takahashi, H., Wu, C.-E., Pang, H.-Y., Lee, Y.-H., Enard, W., Pääbo, S., Graybiel, A.M., and Liu, F.-C. (2023) Speech- and language-linked FOXP2 mutation targets protein motors in striatal neurons. Brain, 146:3541-3557 Arasaratnam, C.J., Song, J.J., Yoshida, T., Curtis, M.A., Graybiel, A.M., Faull, R.L.M., and Waldvogel, H.J. (2023) DARPP-32 cells and neuropil define striosomal system and isolated matrix cells in human striatum. J. Comp. Neurol., 531:888-920 Hirokane, K., Nakamura, T., Kubota, Y., Hu, D., Yagi, T., Graybiel, A.M., and Kitsukawa, T. (2023) Emergence of rhythmic chunking in complex stepping of mice. iScience, 26:106765 Xia, M., Agca, B.N., Yoshida, T., Choi, J., Amjad, U., Bose, K., Keren, N., Zukerman, S., Cima, M.J., Graybiel, A.M., and Schwerdt, H.N. (2023) Scalable, flexible carbon fiber electrode thread arrays for three-dimensional probing of neurochemical activity in deep brain structures of rodents. Biosens. Bioelectron., 241:115625 Kim, M.J., Gibson, D.J., Hu, D., Mahar, A., Schofield, C.J., Sompolpong, P., Yoshida, T., Tran, K.T., and Graybiel, A.M. (2023) Dopamine release plateau and outcome signals in dorsal striatum contrast with classic reinforcement learning formulations. bioRxiv, 2023.08.15.553421 Hirokane, K., Nakamura, T., Terashita, T., Kubota, Y., Hu, D., Yagi, T., Graybiel, A.M., and Kitsukawa, T. (2023) Rhythm receptive fields in striatum of mice executing complex continuous movement sequences. bioRxiv, 2023.09.23.559115 Amjad, U., Choi, J., Murray, R., Gibson, D.J., Graybiel, A.M., and Schwerdt, H. (2023) Synchronous measurements of extracellular action potentials and neurochemical activity with carbon fiber electrodes in nonhuman primates. bioRxiv, 2023.12.23.573130 2022 Thomsen, M., Crittenden, J.R., Lindsley, C.W., and Graybiel, A.M. (2022) Effects of acute and repeated administration of the selective M4 PAM VU0152099 on cocaine versus food choice in male rats. Addict. Biol., 27:e13145 Bloem, B., Huda, R., Amemori, K., Abate, A., Krishna, G., Wilson, A., Carter, C.W., Sur, M., and Graybiel, A.M. (2022) Multiplexed action-outcome encoding by striatal striosome-matrix compartments detected with a novel mouse cost-benefit foraging task. Nat. Commun., 13:1541 Crittenden, J.R., Yoshida, T.M. Venu, S., Mahar, A., and Graybiel, A.M. (2022) Cannabinoid receptor 1 is required for neurodevelopment of striosome-dendron bouquets. eNeuro, 9:ENEURO.0318-21.2022 2021 Crittenden, J.R., Gipson, T.A., Smith, A.C., Bowden, H.A., Yildrim, F., Fischer, K.B., Yim, M., Housman, D.E., and Graybiel, A.M. (2021) Striatal transcriptome changes linked to drug-induced repetitive behaviors. Euro. J. Neurosci., 53:2450-2468. Read PDF>> Pedersen, M.L., Ironside, M., Amemori, K.-I., McGrath, C.L., Kang, M.S., Graybiel, A.M., Pizzagalli, D.A., and Frank, M.J. (2021) Computational phenotyping of brain-behavior dynamics underlying approach-avoidance conflict in major depressive disorder. PLoS Comput. Biol., 17:e1008955. Read PDF>> Amemori, S., Graybiel, A.M., and Amemori, K.-I. (2021) Causal evidence for induction of pessimistic decision-making in primates by the network of frontal cortex and striosomes. Front. Neurosci., 15:649167. Read PDF>> Rolle, C.E., Pedersen, M.L., Johnson, N., Amemori, K., Ironside, M., Graybiel, A.M., Pizzagalli, D.A., and Etkin, A. (2021) The role of the dorsal-lateral prefrontal cortex in reward sensitivity during approach-avoidance conflict. Cereb. Cortex, 2021 Aug 31 [Epub ahead of print]. Read PDF>> Crittenden, J.R., Zhai, S., Sauvage, M., Kitsukawa, T., Burguiere, E., Thomsen, M., Zhang, H., Costa, C., Martella, G., Ghiglieri, V., Picconi, B., Pescatore, K.A., Unterwald, E.M., Jackson, W.S., Housman, D.E., Caine, S.B., Sulzer, D., Calabresi, P., Smith, A.C., Surmeier, D.J., and Graybiel, A.M. (2021) CalDAG-GEFI mediates striatal cholinergic modulation of dendritic excitability, synaptic plasticity and psychomotor behaviors. Neurobiol. Dis., 158:105473. Read PDF>> 2020 Amemori, S., Amemori, K.-I., Yoshida, T., Papageorgiou, G.K., Shimazu, H., Desimone, R., and Graybiel, A.M. (2020) Microstimulation of primate neocortex targeting striosomes induces negative decision-making. Euro. J. Neurosci., 51:731-741. (Cover) Read PDF>> Ironside, M., Amemori, K., McGrath, C.L., Pedersen, M.L., Kang, M.S., Amemori, S., Frank, M.J., Graybiel, A.M., and Pizzagalli, D.A. (2020) Approach-avoidance conflict in major depression: Congruent neural findings in human and non-human primates. Biol. Psychiatry, 87:399-408. Read PDF>> Capponi, S., Stöffler, N., Irimia, M., Van Schaik, F.M.A., Ondik, M.M., Biniossek, M.L., Lehmann, L., Mitschke, J., Vermunt, M.W., Creyghton, M.P., Graybiel, A.M., Reinheckel, T., Schilling, O., Blencowe, B.J., Crittenden, J.R., and Timmers, H.Th.M. (2020) Neuronal-specific microexon splicing of TAF1 mRNA is directly regulated by SRRM4/nSR100. RNA Biol., 17:62-74. Read PDF>> Amemori, K., Amemori, S., Gibson, D.J., and Graybiel, A.M. (2020) Striatal beta oscillation and neuronal activity in the primate caudate nucleus differentially represent valence and arousal under approach-avoidance conflict. Front. Neurosci., 14:89. Read PDF>> Ramadi, K.B., Bashyam, A., Frangieh, C.J., Rousseau, E.B., Cotler, M.J., Langer, R., Graybiel, A.M., and Cima, M.J. (2020) Computationally guided intracerebral drug delivery via chronically implanted microdevices. Cell Rep., 31, 107734. Matsushima, A. and Graybiel, A.M. (2020) Combinatorial developmental controls on striatonigral circuits. Cell Rep., 31:107778. Read PDF>> Ramadi, K.B., Dagdeviren, C., Bhagchandani, P., Nunez Lopez, C., Kim, M.J., Langer, R., Graybiel, A.M., and Cima, M.J. (2020) Simultaneous recording and marking of brain microstructures. J. Neural Eng., 17:044001. Read PDF>> Raman, R., Rousseau, E.B., Wade, M., Tong, A., Cotler, M.J., Kuang, J., Aponte Lugo, A., Zhang, E., Graybiel, A.M., White, F.M., Langer, R., and Cima, M.J. (2020) Platform for micro-invasive membrane-free biochemical sampling of brain interstitial fluid. Sci. Adv., 6, eabb0657. Read PDF>> Schwerdt, H.N., Amemori, K., Gibson, D.J., Stanwicks, L.L., Yoshida, T., Bichot, N.P., Amemori1, S., Desimone, R., Langer, R., Cima, M.J., and Graybiel, A.M. (2020) Dopamine and beta-band oscillations differentially link to striatal value and motor control. Sci. Adv., 6, eabb9226. Read PDF>> Friedman, A., Hueske, E., Drammis, S.M., Toro Arana, S.E., Nelson, E.D., Carter, C.W., Delcasso, S., Rodriguez, R.X., Lutwak, H., DiMarco, K.S., Zhang, Q., Rakocevic, L.I., Hu, D., Xiong, J.K., Zhao, J., Gibb, L.G., Yoshida, T., Siciliano, C.A., Diefenbach, T.J., Ramakrishnan, C., Deisseroth, K., and Graybiel, A.M. (2020) Striosomes mediate value-based learning vulnerable in age and Huntington’s model. Cell, 183:918-934. Read PDF>> Schlossmacher, M.G. and Graybiel, A.M. (2020) Conversations with Dr. Oleh Hornykiewicz, founding father of the dopamine era in Parkinson’s: How do you wish to be remembered? Mov. Disord., 35:1922-1932. Read PDF>> Morigaki, R., Lee, J.H., Yoshida, T., Wüthrich, C., Hu, D., Crittenden, J.R., Friedman, A., Kubota, Y., and Graybiel, A.M. (2020) Spatiotemporal up-regulation of mu opioid receptor 1 in striatum of mouse model of Huntington’s disease differentially affecting caudal and striosomal regions. Front. Neuroanat., 14:608060. Read PDF>> Graybiel, A.M. and Matsushima, A. (2020) The ups and downs of the striatum: dopamine biases upstate balance of striosomes and matrix. Neuron, 108:1013-1015. Read PDF>> 2019 Cotler, M.J., Rousseau, E.B., Ramadi, K.B., Fang, J., Graybiel, A.M., Langer, R., and Cima, M.J. (2019) Steerable microinvasive probes for localized drug delivery to deep tissue. Small, 15:e1901459. Read PDF>> 2018 Delcasso, S., Denagamage, S., Britton, Z., and Graybiel, A.M. (2018) HOPE: hybrid-drive combining optogenetics, pharmacology and electrophysiology. Front. Neural Circuits, 12:41. Ramadi, K., Dagdeviren, C., Spencer, K.C., Joe, P., Cotler, M., Rousseau, E., Nunez-Lopez, C., Graybiel, A.M., Langer, R., and Cima, M.J. (2018) Focal, remote-controlled, chronic chemical modulation of brain microstructures. Proc. Natl. Acad. Sci. U S A, 115:7254-7259. Amemori, K., Amemori, S., Gibson, D.J., and Graybiel, A.M. (2018) Striatal microstimulation induces persistent and repetitive negative decision-making predicted by striatal beta-band oscillation. Neuron, 99:829-841. Schwerdt, H.N., Zhang, E., Kim, M.J., Yoshida, T., Stanwicks, L., Amemori, S., Dagdeviren, H. E., Langer, R., Cima, M.J., and Graybiel, A.M. (2018) Cellular-scale probes enable stable chronic subsecond monitoring of dopamine neurochemicals in a rodent model. Commun. Biol., 1:144. Hong, S., Amemori, S., Chung, E., Gibson, D.J., Amemori, K., and Graybiel, A.M. (2018) Predominant striatal input to the lateral habenula in macaques comes from striosomes. Curr. Biol., 29:51-61. Dagdeviren, C., Ramadi, K.B., Joe, P., Spencer, K., Schwerdt, H.N., Shimazu, H., Delcasso, S., Amemori, K.I., Nunez-Lopez, C., Graybiel, A.M., Cima, M.J., and Langer, R. (2018) Miniaturized neural system for chronic, local intracerebral drug delivery. Sci. Transl. Med., 10:eaan2742. Davis, M.I., Crittenden, J.R., Feng, A.Y., Kupferschmidt, D.A., Naydenov, A., Stella, N., Graybiel, A.M., and Lovinger, D.M. (2018) The cannabinoid-1 receptor is abundantly expressed in striatal striosomes and striosome-dendron bouquets of the substantia nigra. PLoS ONE, 13:e0191436. Martiros, N., Burgess, A.A., and Graybiel, A.M. (2018) Inversely active striatal projection neurons and interneurons selectively delimit useful behavioral sequences. Curr. Biol., 28:560-573. Kelly, S.M., Raudales, R., He, M., Lee, J.H., Kim, Y., Gibb, L.G., Wu, P., Matho, K., Osten, P., Graybiel, A.M., and Huang, Z.J. (2018) Radial glial lineage progression and differential intermediate progenitor amplification underlie striatal compartments and circuit organization. Neuron, 99:345-361. 2017 Nakamura, T., Nagata, M., Yagi, T., Graybiel, A.M., Yamamori, T., and Kitsukawa, T. (2017) Learning new sequential stepping patterns requires striatal plasticity during the earliest phase of acquisition. Eur. J. Neurosci., 45:901-911. Schwerdt, H.N., Kim, M.J., Amemori, S., Homma, D., Yoshida, T., Shimazu, H., Yerramreddy, H., Karasan, E., Langer, R., Graybiel, A.M., and Cima, M.J. (2017) Subcellular probes for neurochemical recording from multiple brain sites. Lab Chip, 17:1104-1115. Crittenden, J.R., Lacey, C.J., Weng, F-J., Garrison, C.E., Gibson, D.J., Lin, X., and Graybiel, A.M. (2017) Striatal cholinergic interneurons modulate spike-timing in striosomes and matrix by an amphetamine-sensitive mechanism. Front. Neuroanat., 11:20. Yamanaka, K., Hori, Y., Minamimoto, T., Yamada, H., Matsumoto, N., Enomoto, K., Aosaki, T., Graybiel, A.M., and Kimura, M. (2018) Roles of centromedian parafascicular nuclei of thalamus and cholinergic interneurons in the dorsal striatum in associative learning of environmental events. J. Neural. Transm., 125:501-513. Spencer, K.C., Sy, J.C., Rhamadi, K., Graybiel, A.M., Langer, R., and Cima, M.J. (2017) Characterization of mechanically matched hydrogel coatings to improve the biocompatibility of neural implants. Sci. Rep., 7:1952. Niemz, J., Kliche, S., Pils, M.C., Morrison, E., Manns, A., Freund, C., Crittenden, J.R., Graybiel, A.M., Galla, M., Jånsch, L., and Huehn, J. (2017) The guanine-nucleotide exchange factor CalDAG GEFI fine-tunes functional properties of regulatory T cells. J. Eur. Microbiol. Immunol., 2:112-126. Friedman, A., Homma, D., Bloem, B., Gibb, L.G., Amemori, K., Hu, D., Delcasso, S., Truong, T.F., Yang, J., Hood, A.S., Mikofalvy, K.A., Beck, D.W., Nguyen, N., Nelson, E.D., Toro Arana, S.E., Vorder Bruegge, R.H., Goosens, K.A., and Graybiel, A.M. (2017) Chronic stress alters striosome-circuit dynamics, leading to aberrant decision-making. Cell, 171:1191-1205. (Cell Previews) Schwerdt, H.N., Shimazu, H., Amemori, K.-I., Amemori, S., Tierney, P.L., Gibson, D.J., Hong, S., Yoshida, T., Langer, R., Cima, M.J., and Graybiel, A.M. (2017) Long-term dopamine neurochemical monitoring in primates. Proc. Natl. Acad. Sci. U S A, 114:13260-13265. Bloem, B., Huda, R., Sur, M., and Graybiel, A.M. (2017) Two-photon imaging in mice shows striosomes and matrix have overlapping but differential reinforcement-related responses. eLife, 6:e32353. Kaji, R., Bhatia, K.P., and Graybiel, A.M. (2018) Pathogenesis of dystonia: is it of cerebellar or basal ganglia origin? J. Neurol. Neurosurg. Psychiatry, 89:488-492. 2016 Kalueff, A.V., Stewart, A.M., Song, C., Berridge, K.C., Graybiel, A.M., and Fentress, J.C. (2016) Neurobiology of rodent self-grooming and its value for translational neuroscience. Nat. Rev. Neurosci., 17:45-59. Smith, K.S. and Graybiel, A.M. (2016) Habit formation coincides with shifts in reinforcement representations in the sensorimotor striatum. J. Neurophysiol., 115:1487-1498. Smith, K.S. and Graybiel, A.M. (2016) Habit formation. Dialogues Clin. Neurosci., 18:33-43. Friedman, A., Slocum, J.F., Tyulmankov, D., Gibb, L.G., Altshuler, A., Raungwises, S., Shi, Q., Toro Arana, S.E., Beck, D.W., Sholes, J.E.C., and Graybiel, A.M. (2016) Analysis of complex neural circuits with non-linear multi-dimensional hidden state models. Proc. Natl. Acad. Sci. U S A, 113:6538-6543 Chen, Y.-C., Kuo, H.-Y., Bornschein, U., Takahashi, H., Chen, S.-Y., Lu, K.-M., Chen, G.-M., Lin, J.-R., Lee, Y.-H., Chou, Y.-C., Cheng, S.-J., Chien, C.-T., Enard, W., Hevers, W., Pääbo, S., Graybiel, A.M., and Liu, F.-C. (2016) Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2C. Nat. Neurosci., 2016 Sep 5. Correia, S.S., Lee, A., McGrath, A.G., Graybiel, A.M., and Goosens, K.A. (2016) Amygdala-ventral striatum circuit activation decreases long-term fear. eLife, 5:e1266. Crittenden, J.R., Tillberg, P.W., Riad, M.H., Shima, Y., Gerfen, C.R., Curry, J., Housman, D.E., Nelson, S.B., Boyden, E.S., and Graybiel, A.M. (2016) Striosome-dendron bouquets highlight a unique striatonigral circuit targeting dopamine-containing neurons. Proc. Natl. Acad. Sci. U S A, 2016 Sep 19. 2015 Burguière, E., Monteiro, P., Mallet, L., Feng, G., and Graybiel, A.M. (2015) Striatal circuits, habits, and implications for obsessive-compulsive disorder. Curr. Opin. Neurobiol, 30:59-65. Amemori, S., Amemori, K.-I., Cantor, M.L., and Graybiel, A.M. (2015) A non-invasive head-holding device for chronic neural recordings in awake behaving monkeys. J. Neurosci Methods, 240:154-160. Amemori, K.-I., Amemori, S., and Graybiel, A.M. (2015) Motivation and affective judgments differentially recruit neurons in the primate dorsolateral prefrontal and anterior cingulate cortex. J. Neurosci., 35:1939-1953. Newman, H., Liu, F.-C., and Graybiel, A.M (2015) Dynamic ordering of early generated striatal cells destined to form the striosomal compartment of the striatum. J. Comp. Neurol., 523:943-962. Friedman, A., Keselman, M., Gibb, L., and Graybiel, A.M (2015) A multi-stage mathematical approach to automated clustering of high-dimensional noisy data. Proc. Natl. Acad. Sci. U S A, 112:4477-4482. Friedman, A., Homma, D., Gibb, L., Amemori, K., Rubin, S., Hood, A., Riad, M., and Graybiel, A.M (2015) A corticostriatal path targeting striosomes controls decision-making under conflict. Cell, 161:1320-1333. Desrochers, T.M., Amemori, K., and Graybiel, A.M. (2015) Habit learning by naive macaques is marked by response sharpening of striatal neurons representing the cost and outcome of acquired action sequences. Neuron, 87:853-868. Graybiel, A.M. and Grafton, S.T. (2015) The striatum: where skills and habits meet. Cold Spring Harb. Perspect. Biol., 7:a021691. Adamantidis, A. et al. (2015) Optogenetics: 10 years after ChR2 in neurons—views from the community. Nat. Neurosci., 18:1202-1212. Feingold, J., Gibson, D.J., DePasquale, B., and Graybiel, A.M. (2015) Bursts of beta oscillation differentiate postperformance activity in the striatum and motor cortex of monkeys performing movement tasks. Proc. Natl. Acad. Sci. U S A, 112:13687-13692. 2014 Thorn, C.A. and Graybiel, A.M. (2014) Differential entrainment and learning-related dynamics of spike and local field potential activity in the sensorimotor and associative striatum. Graybiel, A.M. and Smith, K.S. (2014) Good habits, bad habits. Sci. Am, 310:38-43. Atallah, H.E., Howe, M.W., McCool, A., and Graybiel, A.M. (2014) Neurons in the ventral striatum exhibit cell-type specific representations of outcome during learning. Neuron, 82:1145-1156. Smith, K.S. and Graybiel, A.M., (2014) Investigating habits: strategies, technologies, and models. Front. Neurosci., 8:39. Crittenden, J.R., Lacey, C.J., Lee, T., Bowden, H.A., and Graybiel, A.M., (2014) Severe drug-induced repetitive behaviors and striatal overexpression of VAChT in ChAT-ChR2-EYFP BAC transgenic mice. Front. Neural Circuits, 8:57. Graybiel, A.M. and Smith, K.S. (2014) Good habits, bad habits. Sci. Am, 310:38-43. Holmes, E.A., Craske, M.G., and Graybiel, A.M. (2014) A call for mental-health science. Nature, 511:287-289. Schreiweis, C., Bornschein, U., Burguiere, E., Kerimoglu, C., Schreiter, S., Dannemann, M., Goyal, S., Hevers, W., Rea, E., French, C.A., Puliyadi, R., Groszer, M., Fisher, S.E., Mundry, R., Winter, C., Pääbo, S., Enard, W., and Graybiel, A.M. (2014) Humanized Foxp2 accelerates making transitions from declarative to procedural learning. Proc. Natl. Acad. Sci. U S A, 111:14253-14258. 2013 Howe, M.W., Tierney, P.L., Sandberg, S.G., Phillips, P.E.M., and Graybiel, A.M. (2013) Prolonged dopamine signalling in striatum signals proximity and value of distant rewards. Nature, 500:575-579. Kahn, I., Knoblich, U., Desai, M., Bernstein, J., Graybiel, A.M., Boyden, E.S., Buckner, R.L., and Moore, C.I. (2013) Optogenetic drive of neocortical pyramidal neurons generates fMRI signals that are correlated with spiking activity. Brain Res., 1511:33-45. Hernandez, L.F., Kubota, Y., Hu, D., Howe, M.W., Lemaire, N., and Graybiel, A.M. (2013) Selective effects of dopamine depletion and L-DOPA therapy on learning-related firing dynamics of striatal neurons. J. Neurosci., 33:4782-4795. Smith, K.S. and Graybiel, A.M. (2013) Using optogenetics to study habits. Brain Res., 1511:102-114. Burguiere, E., Monteiro, P., Feng, G., and Graybiel A.M. (2013) Optogenetic stimulation of lateral orbitofronto-striatal pathway suppresses compulsive behaviors. Science, 340:1243-1246. Smith, K.S. and Graybiel, A.M. (2013) A dual operator view of habitual behavior reflecting cortical and striatal activity dynamics. Neuron, 79:361-374. Kahn, I., Knoblich, U., Desai, M., Bernstein, J., Graybiel, A.M., Boyden, E.S., Buckner, R.L., and Moore, C.I. (2013) Optogenetic drive of neocortical pyramidal neurons generates fMRI signals that are correlated with spiking activity. Brain Res., 1511:33-45. 2012 Feingold, J., Desrochers, T.M., Fujii, N., Harlan, R., Tierney, P.L., Shimazu, H., Amemori, K.-I., and Graybiel, A.M. (2012) A system for recording neural activity chronically and simultaneously from multiple cortical and sub-cortical regions in non-human primates. J. Neurophysiol., 107:1979-1995. Amemori, K.-I. and Graybiel, A.M. (2012) Localized microstimulation of primate pregenual cingulate cortex induces negative decision-making. Nat. Neurosci., 15:776-785. Fletcher, R.R., Amemori, K.-I., Goodwin, M., and Graybiel, A.M. (2012) Wearable wireless sensor platform for studying autonomic activity and social behavior in non-human primates. 34th International Conference of the IEEE Engineering in Medicine & Biology Society, San Diego, California, August 28 - September 1. Desrochers, T. and Graybiel, A. (2009) FEF neural responses during uninstructed, optimal eye movements in a free-viewing scan task. COSYNE 2009, Feb. 26-Mar. 1, 2009, Salt Lake City, UT. Surmeier, D.J. and Graybiel, A.M. (2012) A feud that wasn't: Acetylcholine evokes dopamine release in the striatum. Neuron, 75:1-3. Smith, K.S., Virkud, A., Deisseroth, K., and Graybiel, A.M. (2012) Reversible on-line control of habitual behavior by optogenetic perturbation of medial prefrontal cortex. Proc. Natl. Acad. Sci. U S A, 109:18932-18937. Lemaire, N., Hernandez, L.F., Hu, D., Kubota, Y., Howe, M.W., and Graybiel, A.M. (2012) Effects of dopamine depletion on LFP oscillations in striatum are task- and learning-dependent and are selectively reversed by L-DOPA. Proc. Natl. Acad. Sci. U S A, 109:18126-18131. Correia, S., Graybiel, A.M., and Goosens, K.A. (2012) Reward learning prevents spontaneous recovery of fear. Program No. 606.05. 2012 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2012. Online. Schreiweis, C., Enard, W., and Graybiel, A.M. (2012) Altered response to d-amphetamine treatment in mice with humanized Foxp2. Program No. 273.09. 2012 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2012. Online. Lemaire, N., Hernandez, L.F., Hu, D., Kubota, Y., Howe, M.W., and Graybiel, A.M. (2012) Effects of local dopamine depletion on LFP oscillations in dorsolateral striatum are task and learning-dependent and are partially reversed by levodopa administration. Program No. 273.08. 2012 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2012. Online. Smith, K.S., Virkud, A., Deisseroth, K., and Graybiel, A.M. (2012) Optogenetic inhibition of infralimbic cortex both blocks and reinstates habits. Program No. 273.07. 2012 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2012. Online. Thorn, C.A. and Graybiel, A.M. (2012) Interneuron and field potential activities in sensorimotor and associative striatum during learning. Program No. 273.06. 2012 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2012. Online. Amemori, K.-I., Amemori, S., and Graybiel, A.M. (2012) Functional clustering of neurons in primate caudate nucleus related to outcome evaluation for approach-avoidance decision-making. Program No. 273.05. 2012 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2012. Online. Amemori, S., Amemori, K.-I., and Graybiel, A.M. (2012) Microstimulation of macaque subgenual anterior cingulate cortex alters approach-avoidance decision-making. Program No. 273.04. 2012 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2012. Online. Atallah, H.E. and Graybiel, A.M. (2012) Optogenetic identification and manipulation of striatal cholinergic interneurons: implications for function. Program No. 273.03. 2012 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2012. Online. Hernandez, L.F., Kubota, Y., Hu, D., Lemaire, N., Howe, M.W., and Graybiel, A.M. (2012) Effects of dopamine depletion and L-DOPA administration on striatal activity are highly task-modulated during maze learning and performance. Program No. 273.02. 2012 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2012. Online. Burguiere, E., Feng, G., and Graybiel, A.M. (2012) Optogenetic stimulation of orbitofrontal cortex alleviates compulsive behavior in Sapap3 mutant mouse. Program No. 273.01. 2012 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2012. Online. 2011 Kahn, I., Desai, M., Knoblich, U., Bernstein, J., Henniger, M., Graybiel, A.M., Boyden, E.S., Buckner, R.L., and Moore, C.I. (2011) Characterization of the functional MRI response temporal linearity via optical control of neocortical pyramidal neurons. J. Neurosci., 31:15086-15091. Desai, M., Kahn, I., Knoblich, U., Bernstein, J., Atallah, H., Kopell, N., Buckner, R.L., Graybiel, A.M., Moore, C.I., and Boyden, E.S. (2011) Mapping brain networks in awake mice using combined optical neural control and fMRI. J. Neurophysiol., 105:1393-1405. Sako, W., Morigaki, R., Kaji, R., Tooyama, I., Okita, S., Kitazato, K., Nagahiro, S., Graybiel, A.M., and Goto, S. (2011) Identification and localization of a neuron-specific isoform of TAF1 in rat brain: implications for neuropathology of DYT3 dystonia. Neuroscience, 189:100-107. Kitsukawa, T., Nagata, M., Yanagihara, D., Tomioka, R., Utsumi, H., Kubota, Y., Yagi, T., Graybiel, A.M., and Yamamori, T. (2011) A novel instrumented multi-peg running wheel system, step-wheel, for monitoring and controlling complex sequential stepping in mice. J. Neurophysiol., 106:479-487. Amemori, K.-I., Gibb, L.G., and Graybiel, A.M. (2011) Shifting responsibly: The importance of striatal modularity to reinforcement learning in uncertain environments. Front. Hum. Neurosci., 5:47. Barnes, T.D., Mao, J., Hu, D., Kubota, Y., Dreyer, A.A., Stamoulis, C., Brown, E.M., and Graybiel, A.M. (2011) Advance-cueing produces enhanced action-boundary patterning of spike activity in the sensorimotor striatum. J. Neurophysiol., 105:1861-1878. Zhao, S., Ting, J., Atallah, H.E., Qiu, L., Tan, J., Gloss, B., Augustine, G., Deisseroth, K., Luo, M., Graybiel, A.M., and Feng, G. (2011) Cell-type-specific optogenetic mice for dissecting neural circuitry function. Nat. Methods, 8:745-752. Howe, M.W., Atallah, H.E., McCool, A., Gibson, D., and Graybiel, A.M. (2011) Habit learning is associated with major shifts in frequencies of oscillatory activity and synchronized spike firing in striatum. Proc. Natl. Acad. Sci. U S A, 108:16801-16808. Graybiel, A.M. and Morris, R.G. (2011) Editorial Overview. Behavioural and cognitive neuroscience. Curr. Opin. Neurobiol., 21:365-367. Crittenden, J.R. and Graybiel, A.M. (2011) Basal ganglia disorders associated with imbalances in the striatal striosomes and matrix compartments. Front. Neuroanat. 5:59. Graybiel, A.M. (2011) The basal ganglia: binding values to action. Presidential Lecture. 2011 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2011. Online. Smith, K.S. and Graybiel, A.M. (2011) Firing dynamics in prefrontal cortical and striatal sites coordinately promote habitual behavior. Program No. 99.17. 2011 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2011. Online. Schreiweis, C., Burguiere, E., Bornschein, U., Goyal, S., Hevers, W., Mundry, R., Enard, W., and Graybiel, A.M. (2011) Humanized Foxp2 alters learning in differently balanced cortico-basal ganglia circuits. Program No. 100.08. 2011 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2011. Online. Howe, M.W., Atallah, H.E., and Graybiel, A.M. (2011) Synchrony of fast spiking interneurons occurs during beta bursts in the nucleus accumbens and emerges with learning. Program No. 99.23. 2011 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2011. Online. Hernandez, L.F., Kubota, Y., Hu, D., and Graybiel, A.M. (2011) Selective effects of dopamine depletion on neuronal subpopulations in the sensorimotor striatum during procedural learning. Program No. 199.17. 2011 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2011. Online. Gibb, L.G., Amemori, K.-I., and Graybiel, A.M. (2011) The striatum as a context-sensitive modular reinforcement learning system adaptable to changing environments. Program No. 99.19. 2011 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2011. Online. Feingold, J., Gibson, D.J., and Graybiel, A.M. (2011) Brief episodes of beta activity in frontal cortex and striatum. Program No. 99.22. 2011 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2011. Online. Burguiere, E., Feng, G., and Graybiel, A.M. (2011) A new conditioning task to study neuronal activity related to compulsive grooming. Program No. 99.21. 2011 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2011. Online. Atallah, H.E., Howe, M.W., and Graybiel, A.M. (2011) Interaction between projection neurons and interneurons in the ventromedial striatum during learning: Combining tetrode recording and optogenetics. Program No. 99.24. 2011 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2011. Online. Amemori, S., Amemori, K.-I., and Graybiel, A.M. (2011) Effects of anxiolytic drug administration on macaque decision-making under approach-avoidance conflict. Program No. 99.18. 2011 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2011. Online. Amemori, K.-I., Amemori, S., and Graybiel, A.M. (2011) Microstimulation of the macaque caudate nucleus induces changes in outcome evaluation for approach-avoidance decisions. Program No. 99.20. 2011 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2011. Online. 2010 Crittenden, J.R., Dunn, D.E., Merali, F.I., Woodman, B., Borkowska, A.E., Frosch, M.P., Bates, G.P., Housman, D.E., Lo, D.C., and Graybiel, A.M. (2010) CalDAG-GEFI down-regulation in the striatum as a neuroprotective change in Huntington's Disease. Hum. Mol. Genet., 19:1756-1765. Graybiel, A.M. (2010) Templates for neural dynamics in the striatum: striosomes and matrisomes. In: Shepherd, G. and Grillner, S., Eds. Handbook of Brain Microcircuits. New York: Oxford University Press, pp. 120-126. Thorn, C.A., Atallah, H., Howe, M., and Graybiel, A.M. (2010) Differential dynamics of activity changes in dorsolateral and dorsomedial striatal loops during learning. Neuron, 66:781-795. Cantuti-Castelvetri, I., Hernandez, L.F., Keller-McGandy, C., Kett, L.R., Landy, A., Hollingsworth, Z.R., Saka, E., Crittenden, J.R., Nillni, E.A., Young, A.B., Standaert, D.G., and Graybiel, A.M. (2010) Levodopa-induced dyskinesia is associated with increased thyrotropin releasing hormone in the dorsal striatum of hemi-parkinsonian rats. PloS ONE, 5:e13861. Desrochers, T.M., Jin, D.Z., Goodman, N.D., and Graybiel, A.M. (2010) Optimal habits can develop spontaneously through sensitivity to local cost. Proc. Natl. Acad. Sci. U S A, 107:20512-20517. Bernstein, J.G., Desai, M., Kahn, I., Atallah, H., Kopell, N., Buckner, R.L., Moore, C.I., Graybiel, A.M., and Boyden, E.S. (2010) Opto-fMRI: Ultra-high resolution causal circuit mapping, and application to analysis of network dynamics. Program No. 106.7. 2010 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2010. Online. Kahn, I., Knoblich, U., Desai, M., Bernstein, J., Graybiel, A.M., Boyden, E.S., Buckner, R.L., and Moore, C.I. (2010) Opto-fMRI: Blood oxygenation level-dependent (BOLD) response is correlated with optically-driven pyramidal spiking activity. Program No. 106.8. 2010 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2010. Online. Crittenden, J.R., Dunn, D.E., Bowden, H.A., Woodman, B., Yim, M.J., Frosch, M.P., Bates, G.P., Housman, D.E., Lo, D.C., and Graybiel, A.M. (2010) Dysregulation of the striatum-enriched signaling molecules, CalDAG-GEFI and CalDAG-GEFII, in Huntington's disease. Hereditary Disease Foundation HD2010: The Milton Wexler Celebration of Life, Cambridge, MA, August 4-7, 2010. Atallah, H.E., Howe, M.W., and Graybiel, A.M. (2010) Dynamic modulation of ensemble activity in the ventromedial striatum during T-maze learning and re-learning. Program No. 708.2. 2010 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2010. Online. Crittenden, J.R., Sauvage, M., Burguiere, E., Yim, M.J., Costa, C., Martella, G., Ghiglieri, V., Zhang, H., Pescatore, K.A., Liu, T., Unterwald, E.M., Picconi, B., Sulzer, D., Calabresi, P., and Graybiel, A.M. (2010) CalDAG-GEFI is required for normal striatum-based egocentric maze learning in mice and the balance between cholinergic and dopaminergic signaling in the striatum. Program No. 380.15. 2010 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2010. Online. Hernandez, L.F., Hu, D., Kubota, Y., and Graybiel, A.M., (2010) L-DOPA modifies task-related firing patterns of projection neurons in the dopamine-depleted striatum during performance of a T-maze task. Program No. 708.22. 2010 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2010. Online. Amemori, K.I. and Graybiel, A.M. (2010) Localized microstimulation of macaque pregenual anterior cingulate cortex increases rejection of cued outcomes in approach-avoidance decision-making. Program No. 306.4. 2010 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2010. Online. Thorn, C.A. and Graybiel, A.M. (2010) Investigating the interaction of model-free and model-based reinforcement learning systems during T-maze learning. Soc. Neurosci. Abstr., 708.1. 2010 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2010. Online. Desrochers, T.M., Jin, D.Z., Goodman, N.D., and Graybiel, A.M. (2010) Uninstructed monkey eye movement patterns driven by reward in a naturalistic free-viewing scan task. Program No. 77.18. 2010 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2010. Online. Smith, K.S. and Graybiel, A.M. (2010) Neural plasticity in infralimbic cortex and dorsolateral striatum associated with habit formation. 10th Triennial Meeting of the International Basal Ganglia Society, Long Branch, NJ, June 20-24, 2010. Thorn, C.A., Howe, M., and Graybiel, A.M. (2010) Simultaneous activation of dorsolateral and dorsomedial striatal loops during T-maze learning. 10th Triennial Meeting of the International Basal Ganglia Society, Long Branch, NJ, June 20-24, 2010. Crittenden, J.R., Yim, M.J., Fischer, K.B., and Graybiel, A.M. (2010) Sensitization and tolerance to amphetamine-induced behaviors in mice are differentially maintained during withdrawal. 10th Triennial Meeting of the International Basal Ganglia Society, Long Branch, NJ, June 20-24, 2010. Schreiweis, C., Goyal, S., Paabo, S., Graybiel, A.M., and Enard, W. (2010) Speech and language evolution in a mouse: Cognitive abilities of humanized Foxp2 mice. Forum of European Neuroscience, Amsterdam, Abstract No.: 024.43 2009 Graybiel, A.M. (2009) Basal ganglia: habit. In: Squire, L., Ed. Encyclopedia of Neuroscience. Oxford: Academic Press, vol. 2, pp. 93-96. Han, X., Qian, X., Bernstein, J.G., Zhou, H.-h., Franzesi, G.T., Stern, P., Bronson, R.T., Graybiel, A.M., Desimone, R., and Boyden, E.S. (2009) Millisecond-timescale optical control of neural dynamics in the nonhuman primate brain. Neuron, 62:191-198. Crittenden, J.R., Cantuti-Castelvetri, I., Saka, E., Keller-McGandy, C.E., Hernandez, L.F., Kett, L.R., Young, A.B., Standaert, D., and Graybiel, A.M. (2009) Dysregulation of CalDAG-GEFI and CalDAG-GEFII predicts the severity of motor side-effects induced by anti-parkinsonian therapy. Proc. Natl. Acad. Sci. U S A, 106:2892-2896. Prerau, M.J., Smith, A.C., Eden, U.T., Kubota, Y., Yanike, M., Suzuki, W., Graybiel, A.M., and Brown, E.N. (2009) Characterizing learning by simultaneous analysis of continuous and binary measures of performance. J. Neurophysiol., 102:3060-3072. Kubota, Y., Liu, J., Hu, D., DeCoteau, W.E., Eden, U.T., Smith, A.C., and Graybiel, A.M. (2009) Stable encoding of task structure coexists with flexible coding of task events in mouse sensorimotor striatum. J. Neurophysiol., 102: 2142-2160. Graybiel, A.M. (2009) Dynamic templates for neuroplasticity in the striatum. In: Iversen, L.L., Iversen, S.D., Dunnett, S.B., and Björklund, A., Eds. Dopamine Handbook. Oxford, UK: Oxford University Press, pp. 333-338. Jin, D.J., Fujii, N., and Graybiel, A.M. (2009) Neural representation of time in cortico-basal ganglia circuits. Proc. Natl. Acad. Sci. U S A, 106:19156-19161. Graybiel, A.M. and Mink, J.W. (2009) The basal ganglia and cognition. In Gazzaniga, M., Ed. The Cognitive Neurosciences IV. Cambridge, MA: MIT Press, pp. 565-585. Pennartz, C.M.A., Berke, J.D., Graybiel, A.M., Ito, R., Lansink, C.S., van der Meer, M., Redish, A.D., Smith, K.S., and Voorn, P. (2009) Corticostriatal interactions during learning, memory processing, and decision making. J. Neurosci., 29:12831-12838. Crittenden, J.R., Fernandez-Hernandez, L., Yim, M., Keller-McGandy, C., Cantuti-Castelvetri, I., Standaert, D.G., and Graybiel, A.M. (2009) Evaluation of the striatum-enriched genes, CalDAG-GEFI and CalDAG-GEFII, for the treatment and prevention of L-DOPA-induced dyskinesias. Michael J. Fox Foundation Parkinson's Disease Therapeutic Conference, New York, NY. Barnes, T.D., Hu, D., Mao, J., Kubota, Y., Howe, M., Jin, D., and Graybiel, A.M. (2009) Comparison of training-induced activity in the dorsolateral striatum during training on three versions of a T-maze task. Program No. 567.11. 2009 Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience, 2009. Online. Desai, M., Bernstein, J., Atallah, H., Kahn, I., Moore, C.I., Kopell, N., Graybiel, A., and Boyden, E. (2009) Integration of optical neural control and high-field fMRI: Towards systematic exploration of functional neural dynamics with 'Opto-fMRI'. Program No. 484.26. 2009 Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience, 2009. Online. Moore, C., Desai, M., Kahn, I., Ishizawa, Y., Brown, E., Buckner, R., and Graybiel, A. (2009) The impact of isofluorane anesthesia on tactile activation of cortex and striatum: High resolution 9.4t fMRI studies in squirrel monkeys. Program No. 198.2. 2009 Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience, 2009. Online. Hernandez, L.F., Hu, D., Kubota, Y., and Graybiel, A.M. (2009) Dopamine depletion produces selective blockade of learning-related plasticity in firing patterns in the sensorimotor striatum of rats trained on a conditional T-maze task. Program No. 661.24. 2009 Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience, 2009. Online. Thorn, C.A. and Graybiel, A.M. (2009) Projection neurons are entrained to different local field frequencies in dorsomedial and dorsolateral striatum. Program No. 567.9. 2009 Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience, 2009. Online. Smith, K.S. and Graybiel, A.M. (2009) Reward devaluation in a T-maze task shows dynamics of stimulus-response habit formation. Program No. 567.10. 2009 Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience, 2009. Online. Nagata, M., Nomura, M., Aoyagi, T., Yamamori, T., Kubota, Y., Graybiel, A.M., and Kitsukawa, T. (2009) Sequential timing control of complex stepping in mice. Program No. 95.19. 2009 Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience, 2009. Online. Feingold, J., DePasquale, B.D., and Graybiel, A.M. (2009) Modulation of beta power in the prefrontal cortex and caudate nucleus of monkeys during self-timed sequential arm movements. Program No. 863.4. 2009 Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience, 2009. Online. Desrochers, T. M., Amemori, K.-I., Jin, D. Z., and Graybiel, A. M. (2009) Monkey eye movement patterns in a free-viewing scan task: reward and reduction of entropy as drives. Program No. 71.14. 2009 Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience, 2009. Online. Crittenden, J.R., Dunn, D.E., Borkowska, A.E., Woodman, B., Merali, F.I., Frosch, M.P., Housman, D.E., Bates, G.P., Lo, D.C., and Graybiel, A.M. (2009) Down-regulation of CalDAG-GEFI is neuroprotective in a Huntington's disease model. Program No. 432.18. 2009 Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience, 2009. Online. Burguiere, E., Kubota, Y., Masliah, E., and Graybiel, A.M. (2009) Dissociation of learning deficits and action initiation deficits in alpha-synuclein over-expression mouse model of Parkinson's disease. Program No. 661.25. 2009 Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience, 2009. Online. Atallah, H.E., Howe, M.H., and Graybiel, A.M. (2009) Dynamic modulation of ensemble activity in the nucleus accumbens during T-maze learning. Program No. 567.12. 2009 Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience, 2009. Online. Amemori, K.-I. and Graybiel, A.M. (2009) Stimulation of the macaque rostral anterior cingulate cortex alters decision in approach-avoidance conflict. Program No. 194.1. 2009 Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience, 2009. Online. Thorn, C. and Graybiel, A. (2009) Projection neurons in medial and lateral striatum show different ensemble patterns during learning. COSYNE 2009, Program No. I-38, Feb. 26-Mar. 1, 2009, Salt Lake City, UT. 2008 Sato, K., Sumi-Ichinose, C. Kaji, R., Ikemoto, K., Nomura, T., Nagatsu, I., Ichinose, H., Ito, M., Sako, W., Nagahiro, S., Graybiel, A.M., and Goto, S. (2008) Differential involvement of striosome and matrix dopamine systems in a transgenic model of dopa-responsive dystonia. Proc. Natl. Acad. Sci. U S A, 105:12551-12556. Graybiel, A.M. (2008) Habits, rituals and the evaluative brain. Ann. Rev. Neurosci., 31:359-387. Saka, E. and Graybiel, A.M. (2005) Striosome-dominant neuronal activity in dorsolateral striatum is correlated with the severity of dyskinesias in a rat model of parkinsomism. 9th International Congress of Parkinson's Disease & Movement Disorders, New Orleans, LA, March 8-9, 2005. Weiss, L.A., Shen, Y., Korn, J.M., Arking, D.E., Miller, D.T., Fossdal, R., Saemundsen, E., Stefansson, H., Ferreira, M.A.R., Green, T., Platt, O.S., Ruderfer, D.M., Walsh, C.A., Altshuler, D., Chakravarti, A., Tanzi, R.E., Stefansson, K., Santangelo, S.L., Gusella, J.F., Sklar, P., Wu, B.-L., and Daly, M. J. (2008) Association between microdeletion and microduplication at 16p11.2 and autism. N.E J. Med., 358:667-675. Tort, A.B.L., Kramer, M.A., Thorn, C., Gibson, D.J., Kubota, Y., Graybiel, A.M., and Kopell, N.J. (2008) Dynamic cross-frequency couplings of local field potential oscillations in rat striatum and hippocampus during performance of a T-maze task. Proc. Natl. Acad. Sci. U S A, 105:20517-20522. Desrochers, T. M., Habenicht, L. M., Gibson, D. J., Feingold, J., and Graybiel, A. M. (2008) Neurons in the frontal eye field respond during uninstructed eye movement performance in a free-moving task. Program No. 855.8. 2008 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2008. Online. Barnes, T. D., Mao, J., Kubota, Y., Hu, D., Stamoulis, C., and Graybiel, A. M. (2008) Role of the dorsolateral striatum in learning a discriminative procedural task that requires short-term memory processes. Program No. 578.8. 2008 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2008. Online. Thorn, C. A., Atallah, H., Howe, M., and Graybiel, A. (2008) Ensemble unit activity differs between lateral and medial striatal regions during T-maze task learning. Program No. 578.7. 2008 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2008. Online. Ninokura, Y. and Graybiel, A. M. (2008) Effects of explicit and implicit instruction of multiple targets in numerical representation in the macaque caudate nucleus. Program No. 472.21. 2008 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2008. Online. Kramer, M. A., Tort, A. B. L., Thorn, C. A., Gibson, D. J., Kubota, Y., Graybiel, A. M., and Kopell, N. (2008) Dynamic cross-frequency couplings of local field potential oscillations in rat striatum and hippocampus during performance of a T-maze task. Program No. 191.4. 2008 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2008. Online. Han, X., Qian, X., Bernstein, J., Zhou, H., Graybiel, A., Desimone, R., and Boyden, E. S. (2008) Millisecond-timescale optical control of specific genetically-targeted neurons and neural circuits in primate cerebral cortex. Program No. 493.10. 2008 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2008. Online. Amemori, K.-I. and Graybiel, A. M. (2008) Enhancement of neuronal activity in the primate anterior cingulate cortex during approach-avoidance conflict. Program No. 590.22. 2008 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2008. Online. Crittenden, J.R., Dunn, D., Merali, F.I., Woodman, B., Bates, G.P., Housman, D.E., Lo, D.C., and Graybiel, A.M. (2008) Down-regulation of the striatum-enriched signaling molecule, CalDAG-GEF1/RasGRP2, is protective in a model of mutant Htt-induced neurodegeneration. Hereditary Disease Foundation, HD2008, Cambridge, MA; August 8-10, 2008. 2007 DeCoteau, W.E., Thorn, C., Gibson, D.J., Courtemanche, R., Mitra, P., Kubota, Y., and Graybiel, A.M. (2007) Oscillations of local field potentials in the rat dorsal striatum during spontaneous and instructed behaviors. J. Neurophysiol., 97:3800-3805. Tippett, L.J., Waldvogel, H.J., Thomas, S.J., Hogg, V.M., van Roon-Mom, W., Synek, B.J., Graybiel, A.M., and Faull, R.L.M. (2007) Striosomes and mood dysfunction in Huntington's disease. Brain, 130:206-221. Pasvolsky, R., Feigelson, S.W., Filic, S.S., Simon, A.J., Tal-Lapidot, G., Grabovsky, V., Crittenden, J.R., Amariglio, N., Safran, M., Graybiel, A.M., Rechavi, G., Ben-Dor, S., Etzioni, A., and Alon, R. (2007) A LAD-III syndrome is associated with defective expression of the Rap-1 activator CalDAG-GEFI in lymphocytes, neutrophils, and platelets. J. Exper. Med., 204:1571-1582. Bergmeier, W., Goerge, T., Wang, H.-W., Crittenden, J.R., Baldwin, A.C.W., Cifuni, S.M., Housman, D.E., Graybiel, A.M., and Wagner, D.D. (2007) Mice lacking the signaling molecule, CalDAG-GEFI, represent a model for leukocyte adhesion deficiency type III. J. Clin. Inves., 117:1699-1707. DeCoteau, W.E., Thorn, C.A., Gibson, D.J., Courtemanche, R., Mitra, P., Kubota, Y., and Graybiel, A.M. (2007) Learning-related coordination of striatal and hippocampal theta rhythms during acquisition of a procedural maze task. Proc. Natl. Acad. Sci. U S A, 104:5644-5649. Crittenden, J.R., Sauvage, M., Cepeda, C., Andre, V., Costa, C., Martella, G., Liu, T., Verma, S., Levine, M., Calabresi, P., Housman, D.E., and Graybiel, A.M. (2007) CalDAG-GEFI modulates behavioral sensitization to psychomotor stimulants and is required for cortico-striatal long-term potentiation. ACNP (American College of Neuropharmacology) Annual Meeting, Dec. 9-13, 2007, Boca Raton, Florida. Feingold, J., Fujii, N., Desrochers-Feledy, T.M., Harlan, R., and Graybiel, A.M. (2007) A method for recording neural activity simultaneously from independently moveable, chronically implanted electrodes in cortical and sub-cortical areas of monkeys. Neural Coding, Computation and Dynamics (NCCD), September 15-18, 2007, Hossegor, France. Thorn, C.A. and Graybiel, A.M. (2007) Medial and lateral striatal LFPs exhibit task-dependent patterns of coherence in multiple frequency bands. Program No. 622.14. 2007 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2007. Online. Desrochers-Feledy, T.M., Feingold, J., Sim, J., Jin, D.Z., and Graybiel, A. M. (2007) Monkeys have behaviorally optimal eye movement patterns in a free-viewing scan task. Program No. 719.2. 2007 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2007. Online. Ninokura, Y. and Graybiel, A.M. (2007) Representation of forthcoming behavioral steps by unit activity in the macaque caudate nucleus during performance of a sequential reaching task. Program No. 662.2. 2007 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2007. Online. Feingold, J., DePasquale, B.D., and Graybiel, A.M. (2007) Modulation of cortical 8-20 Hz power in supplementary motor areas during self-timed sequential arm movements in monkeys. Program No. 664.7. 2007 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2007. Online. Cantuti-Castelvetri, I., Saka, E., Keller-McGandy, C.E., Bouzou, B., Crittenden, J.R., Hernandez-Fernandez, L., Kett, L.R., Hollingsworth, Z.R., Clark, T., Young, A.B., Standaert, D., and Graybiel, A.M. (2007) Striatal thyrotropin releasing hormone is increased in response to chronic L-DOPA treatment in a rat model of Parkinson disease. Program No. 254.11. 2007 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2007. Online. Crittenden, J.R., Cantuti-Castelvetri, I., Saka, E., Fernandez-Hernandez, L., Keller-McGandy, C., Harlan, P., Kett, L. R., Housman, D. E., Young, A. B., and Graybiel, A.M. (2007) The striatal signaling molecule, CalDAG-GEF2, is up-regulated in the dopamine-depleted striatum of hemi-parkinsonian rats. Program No. 371.13. 2007 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2007. Online. Kitsukawa, T., Kubota, Y., Hu, D., Yamamori, Y., and Graybiel, A.M. (2007) Contrasting spike activity in the striatum and motor cortex of mice performing complex stepping patterns in a running wheel. Program No. 622.22. 2007 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2007. Online. Erickson, K.I., Boot, W.R., Basak, C., Neider, M.B., Prakash, R.S., Voss, M.W., Graybiel, A.M., Simons, D.J., Fabiani, M., Gratton, G., and Kramer, A.F. (2010) Striatal volume predicts level of video game skill acquisition. Cereb. Cortex, 11:2522-2530. Feledy, T.M., Feingold, J., Jin, D., and Graybiel, A.M. (2007) Optimal eye-movement paths emerge as monkeys perform a free-viewing scan task. COSYNE07, Salt Lake City, UT, Feb. 22-27, 2007. 2006 Grillner, S. and Graybiel, A.M. (2006) Introduction. In: Grillner, S. and Graybiel, A.M., Eds. Microcircuits: The Interface between Neurons and Global Brain Function. Cambridge, MA: MIT Press, pp. 1-4. Bergman, H., Graybiel, A.M., Kimura, M., Plenz, D., Seung, H.S., Surmeier, D.J., and Wickens, J.R. (2006) Microcircuits, molecules and motivated behavior: microcircuits in the striatum. In: Grillner, S. and Graybiel, A.M., Eds. Microcircuits: The Interface between Neurons and Global Brain Function. Cambridge, MA: MIT Press, pp. 165-191. Critttenden, J.R., Sauvage, M., Hershcovitch, L., Housman, D.E., and Graybiel, A.M. Mice lacking the striatum-enriched signaling molecule, CalDAG-GEFI, do not undergo amphetamine-induced sensitization of stereotypy. Autism Consortium Retreat, Oct. 26, 2006, Cambridge, MA. Crittenden, J.R., Sauvage, M., Picconi, B., Costa, C., Martella, M., Andre, V., Cepeda, C., Levine, M., Calabresi, P. Housman, D.E., and Graybiel, A.M. The striatum-enriched signaling molecule, CalDAG-GEFI, is essential for cortico-striatal LTP and sensitization of drug-induced stereotypies. Cellular and Molecular Treatments of Neurological Diseases, Cambridge, MA 2006. Barnes, T.D., Jin, D.Z., Hu, D., Kubota, Y., and Graybiel, A.M. (2006) Single cell analysis of striatal projection neuron firing recorded as rats learn a procedural T-maze task. Program No. 556.21. 2006 Neuroscience Meeting Planner. Atlanta, GA: Society for Neuroscience, 2006. Online. Crittenden, J.R., Picconi, B., Ghiglieri, V., Calabresi, P., Harlan, P., Housman, D.E., and Graybiel, A.M. (2006) CalDAG-GEFI is required for sensitization to amphetamine-induced stereotypy and corticostriatal LTP, but not for locomotor sensitization and LTD. Program No. 56.5. 2006 Neuroscience Meeting Planner. Atlanta, GA: Society for Neuroscience, 2006. Online. Thorn, C.A., Gibson, D.J., DeCoteau, W.E., Kubota, Y., Mitra, P., and Graybiel, A.M. (2006) Striatal and hippocampal theta rhythms exhibit task-specific coherence relationships that are modulated by learning in a T-maze task. Program No. 352.15. 2006 Neuroscience Meeting Planner. Atlanta, GA: Society for Neuroscience, 2006. Online. Feledy, T.M., Feingold, J., Jin, D.Z., and Graybiel, A.M. (2006) Eye-movement patterns emerge as monkeys perform a free-viewing scan task. Program No. 48.12. 2006 Neuroscience Meeting Planner. Atlanta, GA: Society for Neuroscience, 2006. Online. Bergmeier, W., Crittenden, J.R., Chauhan, A., Fiffath, C.L., Cifuni, S., Housman, D.E., Graybiel, A.M., and Wagner, D.D. (2006) CalDAG-GEFI plays a central role in platelet activation and thrombus formation in injured arterioles and venules. In submission, 7th Annual Conference on Arteriosclerosis, Thrombosis and Vascular Biology, Denver, CO, Apr. 27-29, 2006. 2005 Barnes, T. Kubota, Y., Hu, D., Jin, D.Z., and Graybiel, A.M. (2005) Activity of striatal neurons reflects dynamic encoding and recoding of procedural memories. Nature, 437:1158-1161. Fujii, N. and Graybiel, A.M. (2005) Time-varying covariance of neural activities recorded in striatum and frontal cortex as monkeys perform sequential-saccade tasks. Proc. Natl. Acad. Sci. U S A, 102:9032-9037. Boraud, T., Brown, P., Goldberg, J.A., Graybiel, A.M., and Magill, P.J. (2005) Oscillations in the basal ganglia: The good, the bad, and the unexpected. In: Bolam, J.P., Ingham, C.A., and Magill, P.J., Eds. The Basal Ganglia VIII, Springer Science and Business Media: New York, NY, pp. 3-24. Bernardi, B., Guidetti, G.F., Campus, F., Crittenden, J.R., Graybiel, A.M., Balduini, C., and Torti, M. (2005) The small GTPase Rap1b regulates the cross-talk between platelet integrin _2_1 and integrin _IIb_3. Blood, 107:2728-2735. Graybiel, A.M. (2005) The basal ganglia: learning new tricks and loving it. Curr. Opin. Neurobiol., 15:638-644. Barnes, T.D., Kubota, Y., Hu, D., Jin, D.Z., and Graybiel, A.M. (2005) Successive reorganizations of activity of striatal projection neurons during learning, unlearning and relearning of a procedural task. Program No. 400.15. 2005 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2005. Online. Sauvage, M., Crittenden, J.R., DeCoteau, W.E., Smith, C., Housman, D.E., and Graybiel, A.M. (2005) CalDAG-GEFI and striatum plasticity: CalDAG-GEFI is critical for behavioral sensitization to amphetamine. Program No. 1030.17. 2005 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2005. Online. Crittenden, J.R., Costa, C., Martella, G., Calabresi, P., Harlan, P., Sauvage, M., Housman, D.E., and Graybiel, A.M. (2005) CalDAG-GEFI is critical for striatal plasticity. Program No. 1030.18. 2005 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2005. Online. Graybiel, A.M., Fujii, N., and Jin, D.Z. (2005) Representation of time and states in the macaque prefrontal cortex and striatum during sequential saccade tasks. Program No. 400.7. 2005 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2005. Online. Plotkin, J., Cepeda, C., Andre, V.M., Wu, N., Kleiman-Weiner, M., Yamazaki, I., Graybiel, A.M., Crittenden, J.R., and Levine, M.S. (2005) Enhanced AMPA receptor function in CalDAG-GEFI-deficient mice. Program No. 1030.19. 2005 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2005. Online. 2004 Smith, A.C., Frank, L.M., Wirth, S., Yanike, M., Hu, D., Kubota, Y., Graybiel, A.M., Suzuki, W.A., and Brown, E.N. (2004) Dynamic analysis of learning in behavioral experiments. J. Neurosci., 24:447-461. Saka, E., Goodrich, C., Harlan, P., Madras, B., and Graybiel, A.M. (2004) Repetitive behaviors in monkeys are linked to specific striatal activation maps. J. Neurosci. 24:7557-7565. Crittenden, J.R., Bergmeier, W., Zhang, Y., Piffath, C.L., Liang, Y., Wagner, D.D., Housman, D.E., and Graybiel, A.M. (2004) CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation. Nature Med. 10:982-986. Saka, E. and Graybiel, A.M. (2004) Pathophysiology of Tourette syndrome: striatal pathways revisited. Brain Dev., 25 Suppl 1:S15-S19. Graybiel, A.M. (2004) Network-level neuroplasticity in cortico-basal ganglia pathways. Parkinsonism Relat. Disord., 10:293-296. Prerau, M.A., Kubota, Y., Graybiel, A., and Brown, E.N. (2004) Estimated learning from simultaneously recorded continuous and discrete measures of performance. Program No. 922.22. 2004 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2004. Online. Kubota, Y., Liu, J., DeCoteau, W.E., and Graybiel, A.M. (2004) Sub-populations of mouse striatal neurons exhibit response plasticity during successive training on two procedural T-maze tasks. Program No. 70.5. 2004 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2004. Online. Fujii, N. and Graybiel, A.M. (2004) Temporal co-modulation of local field potentials (LFPs) in the macaque caudate nucleus and prefrontal cortex. Program No. 186.3. 2004 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2004. Online. Feingold, J., Fujii, N., and Graybiel, A.M. (2004) Monkeys use their eyes to plan an upcoming sequence of arm movements. Program No. 191.11. 2004 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2004. Online. DeCoteau, W.E., Mao, J., Gibson, D.J., Courtemanche, R., Kubota, Y., and Graybiel, A.M. (2004) Striatal theta-gamma local field potential oscillations coordinate with hippocampus rhythms in behaviorally selective patterns. Program No. 70.4. 2004 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2004. Online. Graybiel, A.M., Courtemanche, R., DeCoteau, W., and Kubota, Y. (2004) Oscillations in LFP activity are prominent in the striatum of monkeys and rats and are subject to task-dependent modulations. IBAGS 8th Triennial Meeting, Crieff, Scotland, September 5-9, 2004. 2003 Courtemanche, R., Fujii, N., and Grayiel, A.M. (2003) Synchronous, focally modulated _-band oscillations characterize local field potential activity in the striatum of awake behaving monkeys. J. Neurosci., 23:11741-11752. Fujii, N. and Graybiel, A.M. (2003) Representation of action sequence boundaries by macaque prefrontal cortical neurons. Science, 301:1246-1249. Graybiel, A.M. and Saka, E. (2003) The basal ganglia and the control of action. In: The New Cognitive Neurosciences, 3rd Ed., M.S. Gazzaniga, Ed. Cambridge, MA: MIT Press, pp. 495-510. Graybiel, A.M. (2003) Learning and memory mechanisms of the basal ganglia: plasticity in cortico-basal ganglia loops. In: Instituto Juan March de Estudios e Investigaciones. Workshop on Neuronal Degeneration and Novel Therapeutic Approaches in Parkinson's Disease, p 18: Madrid: Ediciones Peninsular. Smith, A.C., Frank, L.M., Wirth, S., Yanike, M., Hu, D., Kubota, Y., Graybiel, A.M., Suzuki, W.A., and Brown, E.N. (2003) Dynamic analysis of learning in behavioral experiments. Program No. 834.13. 2003 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2003. Online. Madras, B.K., Goodrich, C.M., Topcuoglu, E.S., and Graybiel, A. (2003) Cocaine-induced behaviors in squirrel monkeys change with repeated exposure. Program No. 135.7. 2003 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2003. Online. Fujii, N. and Graybiel, A.M. (2003) Representation of action boundaries by neurons in the prefrontal cortex of the macaque monkey. Program No. 919.10. 2003 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2003. Online. Kubota, Y., Liu, J., DeCoteau, W.E., and Graybiel, A.M. (2003) Learning-related plasticity in the mouse striatum during successive training on two versions of procedural T-maze tasks. Program No. 704.1. 2003 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2003. Online. Courtemanche, R. Fujii, N., and Graybiel, A.M. (2003) Synchrony and focalization of striatal local field potential oscillations in macaque monkeys performing oculomotor saccade tasks. Program No. 390.8. 2003 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2003. Online. Mao, J.-B., Kubota, Y., Smith, A.C., Brown, E.N., and Graybiel, A.M. (2003) Development of signals predictive of behavioral outcome during procedural learning in the rat. Program No. 704.2. 2003 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2003. Online. Graybiel, A.M. and Kubota, Y. (2003) Understanding corticobasal ganglia networks as part of a habit formation system. In: Mental and Behavioral Dysfunction in Movement Disorders, M.-A. B édard, Y. Agid, S. Chouinard, S. Fahn, A.D. Korczyn, and P. Lespérance, Eds. Totowa, NJ: Humana, pp. 51-57. 2002 Brown, L.L., Feldman, S.M., Smith, D.M., Cavanaugh, J.R., Ackermann, R.F., and Graybiel, A.M. (2002) Differential metabolic activity in the striosome and matrix compartments of the rat striatum during natural behaviors. J. Neurosci., 22:305-314. Canales, J.J., Capper-Loup, C., Hu, D., Choe, E.S., Upadhyay, U., and Graybiel, A.M. (2002) Shifts in striatal responsivity evoked by chronic stimulation of dopamine and glutamate systems. Brain, 125:2353-2363. Graybiel, A.M. Guide to the anatomy of the brain: the basal ganglia. (2002) In: Encyclopedia of Learning and Memory, 2nd Ed., J.H. Byrne, Ed. New York: MacMillan, in press. Capper-Loup, C., Canales, J.J., Kadaba, N., and Graybiel, A.M. (2002) Concurrent activation of dopamine D1 and D2 receptors required to evoke neural and behavioral phenotypes of cocaine sensitization. J. Neurosci., 22:6218-6227. Saka, E., Iadarola, M., Fitzgerald, D.J., and Graybiel, A.M. (2002) Local circuit neurons in the striatum regulate neural and behavioral responses to dopaminergic stimulation. Proc. Natl. Acad. Sci. U S A, 99:9004-9009. Blazquez, P., Fujii, N., Kojima, J., and Graybiel, A.M. (2002) A network representation of response probability in the striatum. Neuron, 33:973-982. DeCoteau, W.E., Courtemanche, R., Kubota, Y., and Graybiel, A.M. (2002) Anti-phase theta-range oscillations in striatum and hippocampus recorded in rats during T-maze task performance. Program No. 765.6. 2002 Neuroscience Meeting Planner. Orlando, FL: Society for Neuroscience, 2002. Online. Kubota, Y., DeCoteau, W.E., Liu, J., and Graybiel, A.M. (2002) Task-related activity in the medial striatum during performance of a conditional T-maze task. Program No. 765.7. 2002 Neuroscience Meeting Planner. Orlando, FL: Society for Neuroscience, 2002. Online. Saka, E., Harlan, P., Madras, B., and Graybiel, A.M. (2002) Chronic cocaine exposure induced neuronal responses changes in primate caudate and putamen. Program No. 264.9. 2002 Neuroscience Meeting Planner. Orlando, FL: Society for Neuroscience, 2002. Online. Jog, M.S., Connolly, C.I., Kubota, Y., Iyengar, D.R., Garrido, L., Harlan, R., and Graybiel, A.M. (2002) Tetrode technology: Advances in implantable hardware, neuroimaging, and data analysis techniques. J. Neurosci. Methods, 117:141-152. Graybiel, A.M. and Blazquez, P.M. (2002) Adjusting behavior to context: striatal network functions in learning and memory. In: Catecholamine Research: From Molecular Insights to Clinical Medicine, T. Nagatsu, R. Nabeshima, R. McCarthy, and D.D. Goldstein, Eds. New York: Kluwer Academic/Plenum Publishers, pp. 361-364. Graybiel, A.M. and Saka, E. (2002) Hox genes and obsessive grooming: a genetic basis for obsessive grooming. Neuron, 33:1-2. 2001 Djurfeldt, M., Kubota, Y., Hu, D., DeCoteau, W.E., and Graybiel, A.M. (2001) Changes in correlated activity in the rat sensorimotor striatum during learning of a T-maze task. Program No. 514.10. 2001 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2001. Online. Saka, E., Harlan, P., Fitzgerald, D.J., Iadarola, M., and Graybiel, A.M. (2001) Ablation of cholinergic and somatostatinergic interneurons in the striatum by substance P-linked pseudomonas exotoxin (SP-PE35) leads to changes in striosome-matrix excitability. Program No. 826.17. 2001 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2001. Online. Courtemanche, R., Fujii, N., and Graybiel, A.M. (2001) Local field potential oscillations in the awake macaque striatum. Program No. 67.3. 2001 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2001. Online. Blazquez, P.M., Fujii, N., DeCoteau, W.E., and Graybiel, A.M. (2001) Tonically active neurons in the primate striatum have responses that correlate with the probability of behavioral response in reward and aversive Pavlovian conditioning and habituation. Program No. 514.8. 2001 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2001. Online. Brown, L.L. and Graybiel, A.M. (2001) Preferential activation of the striatal matrix compartment during natural walking. Program No. 68.2. 2001 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2001. Online. Hu, D., Kubota, Y., and Graybiel, A.M. (2001) Successive resculpting of task-related activity patterns in the striatum during action-sequence procedural learning, extinction and relearning. Program No. 514.9. 2001 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2001. Online. Fujii, N. and Graybiel, A.M. (2001) Contrasting neuronal activity during sequential oculomotor behavior between lateral prefrontal cortex and frontal eye field. Program No. 729.16. 2001 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2001. Online. Djurfeldt, M., Ekeberg, Ö., and Graybiel, A.M. (2001) Cortex-basal ganglia interaction and attractor states. Neurocomputing, 38-40:573-579. Toki, S., Kawasaki, H., Tashiro, N., Housman, D.E., and Graybiel, A.M. (2001) Guanine nucleotide exchange factors CalDAG-GEFI and CalDAG-GEFII are colocalized in striatal projection neurons. J. Comp. Neurol., 437:398-407. Matsumoto, N., Minamimoto, T, Graybiel, A.M., and Kimura. M. (2001) Neurons in the thalamic CM-Pf complex supply striatal neurons with information about behaviorally significant sensory events. J. Neurophysiol., 85:960-976. Graybiel, A.M. and Canales, J.J. (2001) The neurobiology of repetitive behaviors: clues to the neurobiology of Tourette syndrome. In: Tourette Syndrome and Related Disorders, Cohen, D.J., Goetz, C. , and Jankovic, J., Eds. Philadelphia: Lippincott-Williams & Wilkins, pp. 123-131. 2000 Fujii, N., Blazquez, P., and Graybiel, A.M. (2000) Performance of repetitive tasks induces modulation of neuronal activity in the supplementary eye field and striatum in macaque monkey. Program No. 360.1. 2000 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2000. Online. DeCoteau, W.E., Hu, D., Kubota, Y., and Graybiel, A.M. (2000) Striatal lesions impair performance of a T-maze procedural learning task in rats. Program No. 254.19. 2000 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2000. Online. Kawasaki, H., Toki, S., Matsuda, M., Tashiro, N., Housman, D.E., and Graybiel, A.M. (2000) Expression of Rap1-targeting cAMP-GEFI and cAMP-GEFII in rat brain. Program No. 724.1. 2000 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2000. Online. Kubota, Y., Hu, D., DeCoteau, W.E., Harlan, R., and Graybiel, A.M. (2000) Multi-neuronal activity in mouse striatum recorded chronically during T-maze learning. Program No. 254.13. 2000 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2000. Online. Blazquez, P., Kojima, J., Fujii, N., Courtemanche, R., and Graybiel, A.M. (2000) Aversive conditioning and habituation as well as reward conditioning modify the activity of tonically active neurons in the macaque striatum. Program No. 254.14. 2000 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2000. Online. Graybiel, A.M. and Rauch, S.L. (2000) Toward a neurobiology of obsessive-compulsive disorder. Neuron, 28:343-347. Graybiel, A.M. (2000) Motor and non-motor functions of the basal ganglia. Kinesis, 5:22-26. Graybiel, A.M., Canales, J.J., and Capper-Loup, C. (2000) Levodopa-induced dyskinesias and dopamine-dependent stereotypies: a new hypothesis. Trends Neurosci., 23 (Suppl.):S71-S77. Graybiel, A.M. (2000) The basal ganglia. Curr. Biol., 10:R509-R511. Mochizuki, N., Ohba, Y., Kobayashi, S., Otsuka, N., Graybiel, A.M., Tanaka, S., and Matsuda, M. (2000) Crk activation of JNK via C3G and R-Ras. J. Biol. Chem., 275:12667-12671. Tan, A., Moratalla, R., Lyford, G.L., Worley, P., and Graybiel, A.M. (2000) The activity-regulated cytoskeletal associated protein Arc is expressed in different striosome-matrix patterns following exposure to amphetamine and cocaine. J. Neurochem., 74:2074-2078. Gardier, A.M., Moratalla, R., Cuéllar, B., Sacerdote, M., Guibert, B., Lebrec, H., and Graybiel, A.M. (2000) Interaction between the serotoninergic and dopaminergic systems in d-fenfluramine-induced activation of c-fos and jun B genes in rat striatal neurons. J. Neurochem., 74:1363-1373. Canales, J.J. and Graybiel, A.M. (2000) A measure of striatal function predicts motor stereotypy. Nat. Neurosci., 3:377-383. Canales, J.J. and Graybiel, A.M. (2000) Patterns of gene expression and behavior induced by chronic dopamine treatments. Ann. Neurol., 47(Suppl. 1):S53-S59. 1999 Fujii, N., Kojima, J., Blazquez, P., and Graybiel, A.M. (1999) Learning-dependent modulation of neuronal activity in the macaque supplementary eye field. Soc. Neurosci. Abstr., 25:368. Liu, F.-C. and Graybiel, A.M. (1999) Neural development of the striatal dopamine system. In: The Development of Dopaminergic Neurons, U. di Porzio, R. Pernas-Alonso, and C. Perrone-Capano, Eds. Austin, TX: R.G. Landes, pp. 87-100. Jog, M.S., Kubota, Y., Connolly, C.I., Hillegaart, V., and Graybiel, A.M. (1999) Building neural representations of habits. Science, 286:1745-1749. Holt, D.J., Herman, M.M., Hyde, T.M., Kleinman, J.E., Sinton, C.M., German, D.C., Hersh, L.B., Graybiel, A.M., and Saper, C.B. (1999) Evidence for a deficit in cholinergic interneurons in the striatum in schizophrenia. Neuroscience, 94:21-31. Graybiel, A.M. and Penney, J.B. (1999) Chemical architecture of the basal ganglia. In: Handbook of Chemical Neuroanatomy, Vol. 15: The Primate Nervous System, Part III, F.E. Bloom, A. Björklund and T. Hökfelt, Eds. Amsterdam: Elsevier, pp. 227-284. Damier, P., Hirsch, E.C., Agid, Y., and Graybiel, A.M. (1999) The substantia nigra of the human brain: II. Patterns of loss of dopamine-containing neurons in Parkinson's disease. Brain, 122:1437-1448. Damier, P., Hirsch, E.C., Agid, Y., and Graybiel, A.M. (1999) The substantia nigra of the human brain: I. Nigrosomes and the nigral matrix, a compartmental organization based on calbindin D28K immunohistochemistry. Brain, 122:1421-1436. Berretta, S., Sachs, Z., and Graybiel, A.M. (1999) Cortically driven Fos induction in the striatum is amplified by local dopamine D2-class receptor blockade. Eur. J. Neurosci., 11:4309-4319. Matsumoto, N., Hanakawa, T., Maki, S., Graybiel, A.M., and Kimura, M. (1999) Nigrostriatal dopamine system in learning to perform sequential motor tasks in a predictive manner. J. Neurophysiol., 82:978-998. Kubota, Y., Jog, M.S., Connolly, C., and Graybiel, A.M. (1999) Cross-correlational analysis of neuronal activity in the rat striatum during T-maze procedural learning. Soc. Neurosci. Abstr., 25:1384. Toki, S., Kawasaki, H., Matsuda, M., Housman, D.E., and Graybiel, A.M. 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(1978) Organization of the nigrotectal connection: an experimental tracer study in the cat. Brain Res., 143:339-348. Graybiel, A.M., Ahmad-Mirza, R. and Elde, R.P. (1981) Somatostatin-like immunoreactivity characterizes neurons of the nucleus reticularis thalami in the cat. Anat. Rec., 199:99A. 1980 Olson, C.R. and Graybiel, A.M. (1980) Sensory maps in the claustrum of the cat. Nature, 228:479-481. Berson, D.M. and Graybiel, A.M. (1980) Some cortical and subcortical fiber projections to the accessory optic nuclei in the cat. Neuroscience, 5:2203-2217. Brown, B.L. and Graybiel, A.M. (1983) Zonal organization in the cerebellar vermis of the cat. Anat. Rec., 205:25A. Graybiel, A.M. and Berson, D.M. (1980) Autoradiographic evidence for a projection from the pretectal nucleus of the optic tract to the dorsal lateral geniculate complex in the cat. Brain Res., 195:1-12. Graybiel, A.M. and Ragsdale, Jr., C.W. (1980) Clumping of acetylcholinesterase activity in the developing striatum of the human fetus and young infant. Proc. Natl. Acad. Sci. U S A, 77:1214-1218. Graybiel, A.M. and Berson, D.M. (1980) Histochemical identification and afferent connections of subdivisions in the lateralis posterior-pulvinar complex and related thalamic nuclei in the cat. Neuroscience, 5:1175-1238. Kaiserman-Abramof, I.R., Graybiel, A.M., and Nauta, W.J.H. (1980) The thalamic projection to cortical area 17 in a congenitally anophthalamic mouse strain. Neuroscience, 5:41-52. Olson, C.R. and Graybiel, A.M. (1980) Sensory regions of the cat's claustrum: An anatomical and physiological study. Soc. Neurosci. Abstr., 6:123. Graybiel, A.M., Ragsdale, C.W., Jr., Yoneoka, E.S. and Elde, R.P. (1980) Opioid peptides, substance P and somatostatin in the striatum: An immunohistochemical study in the cat and kitten. Soc. Neurosci. Abstr., 6:342. Moon Edley, S. and Graybiel, A.M. (1980) Connections of the nucleus tegmenti pedunculopontinis, pars compacta (TPc) in cat. Anat. Rec., 196:129A. 1979 Graybiel, A.M. and Ragsdale, Jr., C.W. (1979) Fiber connections of the basal ganglia. In: Development and Chemical Specificity of Neurons. M Cuénod; G.W. Kreutzberg; and F.E. Bloom, Eds. Amsterdam: Elsevier, pp. 239-283. Graybiel, A.M. (1979) Some patterns of connectivity in the central nervous system: a tribute to Rafael Lorente de Nó. In: Integration in the Nervous System, D.P.C. Lloyd, R. Lorente de Nó, V.J. Wilson and H. Asanuma, Eds. Tokyo: Igaku-Shoin, pp. 69-96. Graybiel, A.M., Ragsdale, Jr., C.W., and Moon Edley, S. (1979) Compartments in the striatum of the cat observed by retrograde cell labeling. Exp. Brain Res., 34:189-195. Graybiel, A.M. (1979) Periodic-compartmental distribution of acetylcholinesterase in the superior colliculus of the human brain. Neuroscience, 4:643-650. Langer, T.P., Kaneko, C.R.S. and Graybiel, A.M. (1979) Efferent projections of the pontine oculomotor pauser region in the cat. Soc. Neurosci. Abstr., 55:374. Graybiel, A.M., Berson, D.M., Langer, T.P. and Colby, C.L. (1979) A pretectal projection to the dorsal lateral geniculate complex in the cat. Soc. Neurosci. Abstr., 5:787. Ragsdale, C.W., Jr. and Graybiel, A.M. (1979) Striosomal organization of the caudate nucleus: III. Distribution of afferents from the frontal cortex of the cat. Soc. Neurosci. Abstr., 5:79. Ragsdale, C.W., Jr. and Graybiel, A.M. (1979) Acetylcholinesterase staining in the striatum of the fetal and neonatal cat. Neurosci. Lett. (Suppl. 3), S26. 1978 Graybiel, A.M. and Ragsdale, Jr., C.W. (1978) Histochemically distinct compartments in the striatum of human, monkey, and cat demonstrated by acetylthiocholinesterase staining. Proc. Natl. Acad. Sci. U S A, 75:5723-5726. Berson, D.M. and Graybiel, A.M. (1978) Parallel thalamic zones in the LP-pulvinar complex of the cat identified by their afferent and efferent connections. Brain Res., 147:139-148. Graybiel, A.M. (1978) A satellite system of the superior colliculus: the parabigeminal nucleus and its projections to the superficial collicular layers. Brain Res., 145:365-374. Graybiel, A.M. (1978) A stereometric pattern of distribution of acetylthiocholinesterase in the deep layers of the superior colliculus. Nature, 272:539-541. Graybiel, A.M. (1978) Connections of the basal ganglia: a general survey. Development and Chemical Specificity of Neurons, Schatzalp/Davos, Switzerland, 11-15 September, 1978. Berson, D.M. and Graybiel, A.M. (1978) Thalamo-cortical projections and histochemical identification of subdivisions of the LP-pulvinar complex in the cat. Soc. Neurosci. Abstr., 4:620. Edley, S.M., Graybiel, A.M. and Ragsdale, C.W., Jr. (1978) Striosomal organization of the caudate nucleus: II. Evidence that neurons in the striatum are grouped in highly branched mosaics. Soc. Neurosci. Abstr., 4:47. Graybiel, A.M. and Ragsdale, C.W., Jr. (1978) Striosomal organization of the caudate nucleus: I. Acetylcholinesterase histochemistry of the striatum in the cat, rhesus monkey and human being. Soc. Neurosci. Abstr., 4:44. 1977 Graybiel, A.M. (1977) Basal ganglia in health and disease. In: Society for Neuroscience, 6th Annual Meeting, Summaries of Symposia (BIS Conference Report No. 45). Los Angeles: Brain Information Service, pp. 41-45. Graybiel, A.M. (1977) Organization of oculomotor pathways in the cat and rhesus monkey. In: Control of Gaze by Brain Stem Neurons, R.G. Baker and A. Berthoz, Eds. Amsterdam: Elsevier, pp. 79-88. Graybiel, A.M. (1977) Direct and indirect preoculomotor pathways of the brainstem: an autoradiographic study of the pontine reticular formation in the cat. J. Comp. Neurol., 175:37-78. Langer, T., Sherk, H. and Graybiel, A.M. (1977) The pathway from the cat's superior colliculus to the parabigeminal nucleus: A study of its cells of origin. Soc. Neurosci. Abstr., 3:566. 1976 Graybiel, A.M. (1976) Evidence for banding of the cat's ipsilateral retinotectal connection. Brain Res., 114:318-327. Gould, B.B. and Graybiel, A.M. (1976) Afferents to the cerebellar cortex in the cat: evidence for an intrinsic pathway leading from the deep nuclei to the cortex. Brain Res., 110:601-611. Graybiel, A.M. (1976) Evidence for a lateral-tegmental projection to the superficial collicular layers and to paramedian midbrain regions in the cat. Anat. Rec., 184:416. 1975 Graybiel, A.M. (1975) Anatomical organization of retinotectal afferents in the cat: an autoradiographic study. Brain Res., 96:1-23. Graybiel, A.M. (1975) Anatomical pathways in the brain stem oculomotor system. In: Eye Movements and Movement Perception, J. Lott Brown, Ed. Rochester, NY: Center for Visual Science, pp. 37-38. Graybiel, A.M. (1975) Wallerian degeneration and anterograde tracer methods. In: The Use of Axonal Transport for Studies of Neuronal Connectivity, W.M. Cowan and M. Cuénod, Eds. Amsterdam: Elsevier, pp. 174-216. Kaiserman-Abramof, I.R., Graybiel, A.M. and Nauta, W.J.H. (1975) Neural connections of area 17 in an anophthalmic mouse strain. Soc. Neurosci. Abstr., 1:102. Graybiel, A.M. and Sciascia, T.R. (1975) Origin and distribution ofnigrotectal fibers in the cat. Soc. Neurosci. Abstr., 1:174. 1974 Graybiel, A.M. and Hartwieg, E.A. (1974) Some afferent connections of the oculomotor complex in the cat: an experimental study with tracer techniques. Brain Res., 81:543-551. Graybiel, A.M. (1974) Visuo-cerebellar and cerebello-visual connections involving the ventral lateral geniculate nucleus. Exp. Brain Res., 20:303-306. Graybiel, A.M. and Devor, M. (1974) A microelectrophoretic delivery technique for use with horseradish peroxidase. Brain Res., 68:167-173. Graybiel, A.M. (1974) Studies on the anatomical organization of posterior association cortex. In: The Neurosciences: Third Study Program, F.O. Schmitt and F.G. Worden, Eds. Cambridge: MIT, pp. 205-214. Graybiel, A.M. (1974) Some efferents of the pretectal region in the cat. Anat. Rec., 178:365. Graybiel, A.M. (1974) Some afferent connections of the oculomotor cortex in the cat. Soc. Neurosci. Abstr. 1973 Graybiel, A.M., Nauta, H.J.W., Lasek, R.J., and Nauta, W.J.H. (1973) A cerebello-olivary pathway in the cat: an experimental study using autoradiographic tracing techniques. Brain Res., 58:205-211. Graybiel, A.M. (1973) The thalamo-cortical projection of the so-called posterior nuclear group: a study with anterograde degeneration methods in the cat. Brain Res., 49:229-244. Graybiel, A.M., Nauta, H.J.W., Lasek, R.J. and Nauta, W.J.H. (1973) Experimental anatomical evidence for a cerebello-olivary pathway in the cat. Anat. Rec., 175:332. 1972 Graybiel, A.M. (1972) Some ascending connections of the pulvinar and nucleus lateralis posterior of the thalamus of the cat. Brain Res., 44:99-125. Graybiel, A.M. (1972) Some fiber pathways related to the posterior thalamic region in the cat. Brain Behav. Evolution, 6:363-393. Graybiel, A.M. (1972) Some extrageniculate visual pathways in the cat. Invest. Ophthalmol., 11:322-332. 1971 Graybiel, A.M. (1971) Some fiber connections of the posterior thalamus in the cat. Doctoral dissertation, Massachusetts Institute of Technology. Graybiel, A.M. and Nauta, W.J.H. (1971) Some projections of superior colliculus and visual cortex upon the posterior thalamus of the cat. Anat. Rec., 169:328. 1970 Graybiel, A.M. (1970) Some thalamocortical projections of the pulvinar-posterior system of the thalamus in the cat. Brain Res., 22:131-136. Graybiel, A.M. and Held, R. (1970) Prismatic adaptation under scotopic and photopic conditions. J. Exp. Psychol., 85:16-22. Graybiel, A.M. (1970) The cortical projection of the pulvinar-posterior complex of the thalamus in the cat. Anat. Rec., 166:309. Back to top |
Books
Crittenden, J.R. and Graybiel, A.M. (2016) Disease-associated changes in the striosome and matrix compartments of the dorsal striatum. In: Handbook of Basal Ganglia Structure and Function, H. Steiner and K.Y. Tseng, Eds. Amsterdam: Elsevier, pp. 801-821. Bergman H, Graybiel A, Kimura M, Plenz D, Seung HS, Surmeier DJ and Wickens JR. (2005) Microcircuits, molecules and motivated behavior: microcircuits in the striatum. In: Grillner S and Graybiel AM, Eds. The Interface between Neurons and Global Brain Function. Dahlem Workshop Report 93. Cambridge, MA: MIT Press, in press. Boraud T, Brown P, Goldberg JA, Graybiel AM and Magill PJ. (2005) Oscillations in the basal ganglia: The good, the bad, and the unexpected. In: Bolam JP, Ingham CA and Magill PJ, Eds. The Basal Ganglia VIII, Springer Science and Business Media: New York, NY, pp. 3-24. Graybiel AM and Saka E. (2003) The basal ganglia and the control of action. In: The New Cognitive Neurosciences, 3rd Ed., Gazzaniga MS, Ed. Cambridge, MA: MIT Press, pp. 495-510. Graybiel AM and Kubota Y. (2003) Understanding corticobasal ganglia networks as part of a habit formation system. In: Mental and Behavioral Dysfunction in Movement Disorders, Bedard MA, Agid Y, Chouinard S, Fahn S, Korczyn AD and Lesperance P, Eds. Humana, Totowa NJ. Graybiel AM. Guide to the anatomy of the brain: the basal ganglia. (2002) In: Encyclopedia of Learning and Memory, 2nd Ed., Byrne JH, Ed. MacMillan, New York. Graybiel AM and Canales JJ. (2001) The neurobiology of repetitive behaviors: clues to the neurobiology of Tourette syndrome. In Tourette Syndrome and Related Disorders, Advances in Neurology, Vol. 85, Cohen D, Jankovic J, and Goetz C, Eds. (Philadelphia: Lippincott-Williams & Wilkins), pp. 123-131. Liu FC and Graybiel AM. (1999) Neural development of the striatal dopamine system. In: Development of Dopaminergic Neurons, Neuroscience Intelligence Unit 4, di Porzio U, Pernas-Alonso R and Perrone-Capano C. Eds. (Austin, TX: R.G. Landes), pp. 87-100. Graybiel AM and Penney JB. (1999) Chemical architecture of the basal ganglia. In: Handbook of Chemical Neuroanatomy, Vol. 15: The Primate Nervous System, Part III, Bloom FE, Björklund A and Hökfelt T, Eds. (Amsterdam, Elsevier), pp. 227-284. Anderson ME and Graybiel AM. (1999) Basal ganglia and the regulation of movement. In: Encyclopedia of Life Sciences. (London: Macmillan). Liu FC and Graybiel AM. (1998) Dopamine and calcium signal interactions in the developing striatum: Control by kinetics of CREB phosphorylation. In: Catecholamines: Bridging Basic Science with Clinical Medicine, Advances in Pharmacology, Vol. 42, Goldstein DS, Eisenhofer G, and McCarty R, Eds. (San Diego, CA: Academic), pp. 682-686. Kimura M and Graybiel AM, Eds. (1995) Functions of the Cortico-Basal Ganglia Loop. Springer-Verlag, New York. Graybiel AM. (1977) Organization of oculomotor pathways in the cat and rhesus monkey. In: Control of Gaze by Brain Stem Neurons, Developments in Neuroscience, Volume I, Baker R and Berthoz A, Eds., Elsevier, 79-88. Graybiel AM. (1975) Anatomical pathways in the brain stem oculomotor system. In: Eye Movements and Movement Perception, Lott Brown J, Ed., Center for Visual Science, Rochester, NY, 37-8. Graybiel AM. (1975) Wallerian degeneration and anterograde tracer methods. In: The use of Axonal Transport for Studies of Neuronal Connectivity. Cuenod M and Cowan WM, Eds. Elsevier, Amsterdam, 174-216. Graybiel AM. (1973) Studies on the anatomical organization of posterior association cortex. In: The Neurosciences: Third Study Program. F.O. Schmitt and F.G. Worden, eds. MIT Press, Cambridge, 205-14. Graybiel AM. (1972) Some fiber pathways related to the posterior thalamic region in the cat. In: Thalamic structure and Function, Riss W, Ed, Brain Behav & Evol, 6: 363-93. Back to top |